MicroRNAs and genomic instability
نویسندگان
چکیده
منابع مشابه
MicroRNAs, Genomic Instability and Cancer
MicroRNAs (miRNAs) are small non-coding RNA transcripts approximately 20 nucleotides in length that regulate expression of protein-coding genes via complementary binding mechanisms. The last decade has seen an exponential increase of publications on miRNAs, ranging from every aspect of basic cancer biology to diagnostic and therapeutic explorations. In this review, we summarize findings of miRN...
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in the popular tale " Ozma of Oz, " Lyman Frank Baum describes the princess Langwidere, who is capable of interchanging her currently worn head with another one, using a collection of heads stored in a cabinet. Remarkably, she changes her character as well when putting a new head on her neck. in the December 15, 2012 issue of Cell Cycle, Kurt Engeland and colleagues report a similar phenomenon ...
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There is limited understanding of how radiation or chemicals induce genomic instability, and how the instability is epigenetically transmitted to the progeny of exposed cells or organisms. Here, we measured the expression of microRNAs (miRNAs) and DNA methyltransferases (DNMTs) in murine embryonal fibroblasts exposed to ionizing radiation or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), which wer...
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ژورنال
عنوان ژورنال: Seminars in Cancer Biology
سال: 2007
ISSN: 1044-579X
DOI: 10.1016/j.semcancer.2006.10.004